Many DOE activities (civilian research, defense research and development, production and stockpile assurance) entail the production, dissemination, or sharing of information.  The XML family of standards can greatly facilitate the interchange of information (data, metadata, documents, CAD designs,...) among the DOE national labs, DOE, vendors, and the larger scientific community. 

In this talk we describe some of the major prospective applications to realize such XML-mediated information sharing, additional standards and tools required (XMI, metadata registries, ...).  We suggest an agenda of research, standards, and software development to hasten such information sharing.    Applications range from administrative (reporting, budgeting, procurement, etc.) to scientific publication, to CAD design exchange, to metadata/data exchange for scientific and toxics management purposes.