Abstract Details

Diffractive Imaging of Oriented Molecules in the Gas Phase
Abstract ID	BIO-01
Presenter	Jochen  Küpper
Presentation Type	Poster
Full Author List	J. Küpper (1) , H. Stapelfeldt (2) , H. N. Chapman (3) , G. Meijer (1) , others (1,2,3)
Affiliations	(1) Fritz-Haber-Institut der MPG, Berlin, Germany (2) Department of Chemistry, University of Aarhus, Aarhus, Denmark (3) CFEL, DESY, University of Hamburg, Germany
Category	Bio/Life Sciences
Abstract	We have developed techniques to manipulate the motion of large molecules. We exploit static or switched inhomogeneous electric fields to manipulate the translation of large molecules1 and to select quantum states and conformers (structural isomers) of prototypical biomolecules.2 Using strong laser fields, the rotational motion can be controlled and the molecules can be aligned3 or oriented in mixed dc and laser fields. Such conformer and quantum state selected samples of oriented molecules are ideal targets for coherent diffractive imaging using the LCLS. We will discuss the prospects of such benchmark experiments for hard x-ray molecular diffractive imaging.4,5 Such experiments test the general possibility to determine reliable and precise structural information from diffractive imaging using XFEL radiation.
Footnotes	1K Wohlfart, F Grätz, F Filsinger, H Haak, G Meijer, and J Küpper, Alternating-gradient focusing and deceleration of large molecules Phys Rev A 77 031404(R) (2008). 2F Filsinger, U Erlekam, G von Helden, J Küpper, and G Meijer, Selector for structural isomers of neutral molecules, Phys Rev Lett 100 133003 (2008). 3H Stapelfeldt, T Seideman, Colloquium: Aligning molecules with strong laser pulses, Rev Mod Phys 75 543 (2003) 4K J Gaffney, H N Chapman Imaging atomic structure and dynamics with ultrafast X-ray scattering Science 316, 1444 (2007) and references therein 5H. N. Chapman et al, Femtosecond diffractive imaging with a soft-X-ray free-electron laser Nat Phys 2, 839 (2006)
Funding Acknowledgement