Abstract Details
| Protein Nanocrystals, Aerojets and Electronic Damage | |
|---|---|
| Abstract ID | W_Coherent-4 |
| Presenter | John Spence |
| Presentation Type | Coherent X-ray - LCLS |
| Full Author List | J. C. H. Spence and collaborators* (1) |
| Affiliations | (1) Physics, Arizona State University, Tempe, AZ USA 85282 |
| Category | Instrumentation/Development |
| Abstract | A brief review will be given of four projects intended for the LCLS.
1. In collaboration with S. Boutet. M. Bogan and M. Frank, we plan to synchronize our aerojet single-file droplet beam injector with the LCLS. This provides a means of hitting biological samples which require hydration with the femtosecond X-ray pulse. 2. Bragg spot-fading experiments are planned for various pulse durations in order to study the early stages of photodissociation in two-dimensional protein monolayer crystals. 3. Experiments on X-ray diffraction from laser-aligned organic molecules are planned. 4. A new approach to single-shot tomography will be outlined, and a method described for removing multiple scattering artifacts from soft-Xray diffraction patterns. |
| Footnotes | *See authors on the following papers, which describe preliminary work on these experiments.
1. Powder diffraction from a continuous microjet of nanoscale protein crystals. D.A. Shapiro, D. De Ponte, R.B. Doak, P. Fromme, G. Hembree, M. Hunter, S. Marchesini, K. Schmidt, U. Weierstall, J.C.H.Spence. J. Synch. Rad. In press. (2008). IDBR 0555845, CBST. http://arxiv.org/abs/0803.4027. 2. "Triple-beam tomographic femtosecond X-ray diffractive imaging". K. Schmidt, J. Spence, U. Weierstall, D. Starodub, H. Chapman, M. Howells, B. Doak.J. Phys Rev Letts. (2008). In press. 3. "Gas dynamic virtual nozzle for generation of microscopic droplet streams". D. De Ponte, U. Weirstall, D. Starodub, J. Warner, J.C.H.Spence, R.B.Doak. J. Phys D. (2008) In press. http://arxiv.org/abs/0803.4181. 4. "Dose, exposure time and resolution in serial crystallography". D. Starodub, P. Rez, M. Howells, D. Shapiro, H. Chapman, P. Fromme, K. Schmidt, U. Weierstall, R. Doak, J. Spence. J. Synch Res. 15, 62-73 (2008) . |
| Funding Acknowledgement | |